Full name: ribosomal protein L5

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Ska23; Ska<m23Jus>; Skax23; U21RNA

Summary: Predicted to enable RNA binding activity; ubiquitin ligase inhibitor activity; and ubiquitin protein ligase binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in several processes, including positive regulation of aminoacyl-tRNA ligase activity; regulation of cellular protein metabolic process; and ribosome biogenesis. Located in synapse. Is expressed in several structures, including central nervous system; gonad; intestine; sensory organ; and spleen. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 6; T-cell acute lymphoblastic leukemia; and glioblastoma. Orthologous to human RPL5 (ribosomal protein L5). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Broad expression in CNS E11.5 (RPKM 297.0), placenta adult (RPKM 283.2) and 25 other tissues

Gene size: 8484bp

Exon count: 8