CNGB Sequence Archive (CNSA) is a convenient and efficient archiving system of multi-omics data in life science, which provides archiving services for raw sequencing reads and further analyzed results. CNSA follows the international data standards for omics data, and supports online and batch submission of multiple data types such as Project, Sample, Experiment/Run, Assembly, Variation, Metabolism, Single cell, Sequence. Its data submission service can be used as a supplement to the literature publishing process to support early data sharing.

So far, CNSA has archived XXXX TB data, XXX TB public data, XXXX projects, XXXXX samples, XXXXX experiments, and XXXXX runs, and supported XXarticles, XX magazines, XX organizations.

Please view the Statistics for detailed statistics.

CNSA currently accepts metadata or data files of project, sample, experiment/run, assembly, variation, metabolism, single cell and sequence.

Metadata is data that describes an information resource or a data object. For example, metadata of experiment/run refers to a description of experiment/run data, such as sequencing platform, library strategy, etc.; data files of experiment/run refer to files of sequencing reads.

Please click "Submit" on the homepage or “Submission portal” in the navigation bar, select the data type, and follow the page prompts to submit the metadata or data files. Users can view the data upload options in “My service” if they will upload data files. For the FTP upload method, refer to FTP data upload. For the MD5 value calculation, refer to MD5 check. For a simple data submission process, refer to the “CNSA Handbook (simple version in English)”. For detailed data submission process, please refer to “Data Submission”.

Please first download the FTP client, such as the Filezilla FTP client, log in with the ftp server, username and password provided by CNSA, and upload the data files. The FTP server, username and password can be viewed in the data submission process or “My service”. For details on how to upload, please refer to "FTP data upload".

MD5 (Message Digest Algorithm 5) is a hash function which calculates a hash value (MD5 number, 32-digit numbers and letters) of a given file. An MD5 checksum can be computed for a file before and after transfer to verify whether the file was transmitted successfully. For details on how to generate MD5 values, refer to “MD5 check”.

CNGBdb (CNSA) has a standardized data preservation system to the requirements of relevant national laws and regulations, and provides reliable and long-term preservation services for the submitted scientific data. CNGBdb (CNSA) has a comprehensive long-term data preservation plan. CNGBdb (CNSA) applies the latest data preservation techniques (including but not limited to data encryption, data backup, etc.) to ensure that archived data are permanently preserved, and will not be lost due to technological development. For details, please see: Preservation Plan.

CNSA advocates the concept of open sharing and believes that open access to data is crucial for scientific discoveries. In order to promote the sharing and reuse of biological data, CNSA adheres to the TRUST and FAIR principles, offering both public and controlled data management approaches.

Public Data refers to data whose data access manner is "Public". This includes making both the metadata and data files associated with the project publicly available. The public data will be open for access worldwide, allowing users to browse and download. CNSA uses CC BY 4.0 license for public data. Details about CC-BY 4.0 can be found at https://creativecommons.org/licenses/by/4.0/.

If you prefer to manage data in a 'Public' manner, please select the 'Public' option in the data access manner module during the project submission process.

Controlled Data refers to data whose data access manner is "Controlled". That is, the metadata associated with the project will be public and the data files will be controlled. Users can apply for access to Controlled Data.

If you prefer to manage data in a 'Controlled' manner, please select the 'Controlled' option in the data access manner module during the project submission process.

Please click on "My Submission" on the CNSA homepage to view it. In the “Status” column you can view the corresponding submission ID or download the metadata file with accessions.

CNSA will automatically assign numbers, prefixed by CNP (project), CNS (sample), CNSebb (EBB sample), CNX (experimental), CNR (run), CNA (assembly), varc (variation), METM (metabolism), CSE (single cell), etc. Please refer to the "Numbering rules" for specific numbering rules.

StatusExplanation
UnfinishedThe data submission process has not yet reached the final step.
ProcessingThe data submission process has been completed and the data has not been reviewed or in review.
ProcessedThe data has been reviewed and has a release date, but has not reached the release date.
ControlledThe data has been reviewed and has no release date and cannot be made public.
PublicThe data has been reviewed and public on the release date set by the data submitter.

Please click on "My submission" on the CNSA homepage to find the object that needs to be modified, click the “pencil icon” to modify it, the scope of the modifiability and the requirements for the fields can be found in the modification process. Please do not create a new submission to submit similar information for the purpose of modification! Modifications do not affect the reference to assigned accession! If you need to modify the object without pencil icon or delete some objects, you can apply for modification or deletion at datasubs@cngb.org and provide the corresponding accession.

There are three data management manners of CNSA: Public, Controlled and Private. You can choose a data management manner when submitting a project. The release date of the public data and the metadata release date of the controlled data can be set in the project submission process. If you need to modify the release date, please click “My submission” on the CNSA homepage to find out the submission that you need to modify.

1)   If the status of the project is “Unfinished”, click the “pencil icon” in the project “status” column to enter the process to modify the release date.

2)   If the status of the project is "Processing" or "Processed", you can click the date of the “release date” column or "pencil icon" to modify the release date.

3)   If the status of the project is "Public" or "Controlled", please send an email to datasubs@cngb.org to apply for the modification and indicate the project accession and the reason for the change.

1)   If you need to modify the Data access manner, please send an e-mail to datasubs@cngb.org with the project accession number and the reason for the modifications. The data administrator will send the "Application Form for Modification in Data Access Manner" to you.

2)   Please fill in the form carefully, and ensure that all information (including but not limited to the given information) involved in this application for modification of Data access manner and any documents / materials sent to CNGBdb have been strictly reviewed.

3)   Once completed the application, an electronic form (in DOC / DOCX version) and a scanned copy of the signed form, and the required materials such as record-filing form (if necessary) must be e-mailed to datasubs@cngb.org as soon as possible.

4)   Please note that the platform only accepts Data access manner modification application on the basis of the project, and does not accept changes in the data access manner of partial data under the same project number. If you have such needs, please submit two or more projects at the beginning of the data submission.

1)   Material Review:the data administrator (datasubs@cngb.org) will review the submission application, and its consistency with other materials (if any) provided by you. Please note that the review time is generally 5 working days. During the review period, you can continue to submit other data.

2)   Data Review:the data administrator (datasubs@cngb.org) will conduct the data review after the material review is passed. We review the completeness, the correctness, and the relevance of the submitted data. If the submitted data is incorrect, a notification e-mail will be sent to you by the data administrator. Depending on the sample size and the amount of data submitted, the data review takes 5 to 7 working days.

3)   After the review is over, the data administrator will inform you by email that the review is approved or the application is terminated. If the review is passed, your data will be archived as public data, controlled data or private data in accordance with the data access manner you choose.

If your data has been submitted to the CNGBdb-CNSA, you can add the following words to your manuscript to cite the accession number in CNGBdb:

English:

The data that support the findings of this study have been deposited into CNGB Sequence Archive (CNSA) [1] of China National GeneBank DataBase (CNGBdb) [2] with accession number CNPXXXXXXX.

Chinese:

该研究的相关结果数据已收录在国家基因库生命大数据平台(CNGBdb)[2] 的国家基因库序列归档系统(CNSA)[1],项目编号:CNPXXXXXXX。

[1] Guo XQ, Chen FZ, Gao F, et al. CNSA: a data repository for archiving omics data. Database (Oxford). 2020;2020:baaa055. doi:10.1093/database/baaa055.

Endnote Download

[2] Chen FZ, You LJ, Yang F, et al. CNGBdb: China National GeneBank DataBase. Hereditas. 2020;42(08):799-809. doi:10.16288/j.yczz.20-080.

If your data is controlled, please send an email with the project accession to datasubs@cngb.org. If the data is public, you can enter the CNSA project accession directly in the search box on the CNSA homepage and send a link to the searched data detail page to the magazine. Currently we can provide reviewer links of project, sample, experiment/run, assembly, and variant. The reviewer link is valid for 2 months. if you need to postpone, please send an email to datasubs@cngb.org to apply for an extension, and you need to indicate the reviewer link in the email.

1.   You can share your project using the project accession (CNPXXXXXXX). CNSA will automatically generate a project accession (CNPXXXXXXX) after you complete the project submission. The project accession can be found in your "Personal center". This project accession can be searched on the CNSA website after your project is public.

2.   You can share your project with DOI. DOI (Digital Object Identifier) is a permanent and unique digital resource identifier. CNSA will automatically assign a DOI to your project number (e.g. 10.26036/CNPXXXXXXX) after your project is public. You can share your project using this assigned DOI. For more details about DOI, please visit doi.org.

The public data can be searched by entering keywords such as the accession in the search box of the CNSA homepage.

Only public data allows users to download freely. Users can click the “Download” button in the CNSA homepage navigation bar to enter the CNSA FTP download page to download data. You can also enter the data accession in the search box on the home page and enter the search details page to download. When downloading and using publicly available data, please follow the "CNSA User Instructions".

Controlled data refers to data that the metadata associated with the project will be public and the data files will be controlled. Other registered users can apply for access to controlled data to the CNGB data access. Data applicants must use the data after the data submitter have reviewed and approved, and the access or data files will be granted to the data applicant by the data submitter.

If you have any questions or suggestions, feel free to contact datasubs@cngb.org.

Address:China National GeneBank, Jinsha Road, Dapeng District, Shenzhen, China

Tel:0755-33945586

QQ group:894343659

Welcome to scan the code to follow our public number and video number: