The binding of platinum complexes to tuna cytochrome c.
Biochem J, 1982/3/01;201(3):523-6.
Boswell AP, Moore GR, Williams RJ
PMID: 6284122
Impact factor: 3.766
Abstract
The binding of [PtCl4]2- and cis-[PtCl2(NH3)2] to methionine-65 of tuna cytochrome c was investigated by 1H n.m.r. The modification at methionine-65 is shown to cause an extremely small structural perturbation to the protein at the site of modification.
MeSH terms
Animals; Cisplatin; Cytochrome c Group; Magnetic Resonance Spectroscopy; Methionine; Platinum; Platinum Compounds; Protein Binding; Protein Conformation; Tuna
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