[Estimation of GFR from serum creatinine and cystatin C-A comparison of 2 methods in patients with neurogenic bladder due to myelomeningocle (MMC)].
Pol Merkur Lekarski, 2008;24 Suppl 4:119-20.
Drozyńska-Duklas M[1], Zurowska A, Czarniak P, Maternik M
Affiliations
PMID: 18924523
Abstract
unlabelled: Glomerular filtration rate (eGFR) calculated from serum creatinine can be overestimated in patients with muscle mass deficits.
aim: The aim of this study was to compare eGFR calculated from serum levels of creatinine and cystatin C in a group of patients with neurogenic bladder due to MMC.
material and methods: GFR calculations were performed for 67 patients using Schwartz formula for creatinine measured by colorimetric method and Filler formula for cystatin C measured by immunonephelometric method.
results: Statistically significant lower eGFR values were obtained with calculations based on cystatin C levels.
conclusion: Cystatin C is a useful marker for GFR estimations in patients with reduced muscle mass.
MeSH terms
Adolescent; Adult; Child; Child, Preschool; Creatinine; Cystatin C; Cystatins; Female; Glomerular Filtration Rate; Humans; Kidney Function Tests; Male; Meningomyelocele; Urinary Bladder, Neurogenic
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