Marine Life Genome Database (MLGD) is an on-line database aiming to provide a comprehensive knowledge and analysis for the genome of marine lives. We collected the genome, transcriptome and proteome data and information of the marine species that has been sequenced and published so far. These information are organized based on the taxonomy of marine lives and each specie can be searched and viewed in the taxon tree. The information of each specie contains: description, reference, image, genetic information and data. Data sets can be downloaded directly or redirected to the NCBI Genome database, and we will add some on-line analysis tools in the future editions. We highly welcome cooperations to sequence and analyze new marine species for a better understanding of the genomes of marine lives.