KDR

Official symbol

KDR

Official full name

kinase insert domain receptor

Gene ID

3791

Gene type

-

Other name

CD309,FLK1,VEGFR,VEGFR2

Gene location

Gene introduction

Kinase insert domain receptor (KDR) is a gene that encodes a protein that functions as a type III receptor tyrosine kinase of vascular endothelial growth factor (VEGF). The protein regulates VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis, and sprouting. Missense mutations, nonsense mutations, silent mutations, frameshift deletions and insertions, and in-frame deletions are observed in cancers such as intestinal cancer, lung cancer, and skin cancer.

Cancer pathway

-

Related to cancer

-

Alteration in cancer

Related drugs in cancer