Project name: Long-Term Hepatitis B Virus Infection Induces Cytopathic Effects in Primary Human Hepatocytes, and Can be Partially Reversed by Antiviral Therapy

Description: Transcriptomic analysis was then applied to identify genes or pathways that could be rescued by RNAi.Overall design: A combination of two siRNA (siHBV, 100 nM) to degrade all kinds of HBV RNAs (targeting both HBs and HBx sequences) was transfected by commercial reagents at 7 days post HBV infection, and the cells were collected for RNA-seq 6 days later.

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: Medical

Last updated: 2022-01-19