Project name: Gene expression alternations in Shenqi Jiangtang Granule-treated rats kidney

Description: Diabetic rats changes gene exprssion in Shenqi Jiangtang Granule-treated rats kidneyDiabetic nephropathy (DN) is a major microvascular complication of diabetes. In addition to moderating hyperglycemia, Shenqi Jiangtang Granule (SJG) had a beneficial effect on kidney function in a clinical trial. However, the mechanism involved remains unclear. This study was conducted to identify the underlying molecular mechanisms. A diabetic rat model was generated by using a high-fat diet and streptozotocin (STZ) injection. Then, rats were given SJG at dosages of 800 mg/kg/d by gavage for 8 weeks.Overall design: We performed microarray analyses of Shenqi Jiangtang Granule-treated rats kidney

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: ModelOrganism

Last updated: 2019-07-10