Expression profile of the endocrine therapy resistant breast cancer cells LTED depleted of PBX1 or treated with the gamma-secretase inhibitor MRK003
Source: NCBI BioProject (ID PRJNA157103)
Source: NCBI BioProject (ID PRJNA157103)
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Project name: Homo sapiens
Description: Analysis of the response to PBX1 deprivation either using an siRNA approach or using a chemicalcompound indirectly targeting it. Deprivation of PBX1 is hypothesized to be essential for the growth of endocrine therapy resistant breast cancer cells (LTED)Overall design: Total RNA was obtained from cells treated with siPBX1 or a control siRNA. The second set contains RNA from cells treated with MRK003 or a control (DMSO).
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Lupien, Genetics, Dartmouth College
Literatures
- PMID: 23576735
Last updated: 2012-03-29