cis-Expression QTL Analysis of Established Risk Variants for Colorectal Cancer
Source: NCBI BioProject (ID PRJNA145435)
Source: NCBI BioProject (ID PRJNA145435)
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Project name: Homo sapiens
Description: Genome-wide association studies (GWAS) have identified 19 risk variants associated with colorectal cancer. As most of these risk variants reside outside the coding regions of genes, we conducted cis-expression quantitative trait loci (cis-eQTL) analyses to investigate possible regulatory functions on the expression of neighboring genes.Overall design: Forty microsatellite stable and CpG island methylator phenotype-negative colorectal tumors and paired adjacent-normal colon tissues were used for genome-wide SNP and gene expression profiling in our cis-eQTL analyses.This submission represents transcriptome component of study.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Epidemiology Program, University of Hawaii Cancer Center
Last updated: 2011-08-30