Effect of loss of Gfi1b on hematopietic stem cells
Source: NCBI BioProject (ID PRJNA124877)
Source: NCBI BioProject (ID PRJNA124877)
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Project name: Mus musculus
Description: Using Gfi1b conditional mice, deletion of gfi1b in the hematopietic system was induced by injecting MxCre tg Gfi1bfl/fl mice with pIpC. 30 days after injection, Cd150 pos, Cd 48 neg, Lin neg Sca and c-kit pos stem cells were sortrted from Gfi1bfl/fl and Mxcre tg Gfi1bfl/fl mice and analysed. We used the mouse Affymetrix Gene ST Array.Overall design: The study should determine whether loss of Gfi1 alters the gene expression pattern in the hematopietic stem cells.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Hematology, University Hospital Essen
Literatures
- PMID: 20826720
Release date: 2010-09-03
Last updated: 2010-03-05