US28-expressing and mock-transfected stable NIH-3T3 cell lines
Source: NCBI BioProject (ID PRJNA110669)
Source: NCBI BioProject (ID PRJNA110669)
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Project name: Mus musculus
Description: The human cytomegalovirus (HCMV) encodes the chemokine receptor US28 that exhibits constitutive activity. NIH-3T3 cells stably transfected with US28 present a pro-angiogenic and transformed phenotype both in vitro and in vivo.We used gene expression profiling to determine how US28 constitutive activity modulates expression of genes compared to mock-transfected cells.Keywords: Comparison of stably transfected cell linesOverall design: We isolated RNA from two different clonal stable cell lines of NIH-3T3 cells transfected either either mock or US28-WT and analysed these 4 RNA samples using Affymetrix mouse genome arrays.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Martine J Smit/Rob Leurs, Division of Medicinal Chemistry, Faculty of Sciences, Vrije Universiteit Amsterdam, Leiden/Amsterdam Center for Drug Research
Literatures
- PMID: 19318580
Release date: 2009-03-30
Last updated: 2008-11-12