Behavioral and multiomics analysis of three-dimensional clinostat simulated microgravity effect in mice
Source: CNGBdb Project (ID CNP0006448)
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Project name: Three-Dimensional Clinostat Simulated Microgravity Effect in Mice
Description: Eighteen male 10-week-old C57BL/6J mice were randomized into three groups: mice in ordinary cages group (MC, n = 6), survival box for clinostat group (SB, n = 6), and clinostat + survival box group (CS, n = 6). Behavioral experiments (including grip strength experiment, open field test, novel object recognition test, Y Maze, elevated plus maze, tail suspension test, gait analysis, rotarod test, Morris water maze, forced swim test and fear conditioning test), femur micro-CT, brain transcriptomics, serum metabolomics and fecal microbiomics were conducted to evaluate the impact of 3D clinostat simulated microgravity effect.
Data type: Raw sequence reads; Transcriptome or Gene expression; Metabolome
Sample scope: Multiisolate
Relevance: Medical
Submitter: 周澧(Li Zhou); 中国医学科学院医学实验动物研究所
Literatures
  1. PMID: 39962314
Release date: 2024-10-31
Last updated: 2024-10-31
Statistics: 36 samples; 36 experiments; 36 runs; 1 metabolism
Data size: 75.68GB