Modification of RNA polymerase from Escherichia coli by pre-early gene products of bacteriophage T5.
J Virol, 1981/12;40(3):958-62.
McCorquodale DJ, Chen CW, Joseph MK, Woychik R
PMID: 7033565
Impact factor: 6.549
Abstract
RNA polymerase from cells of Escherichia coli infected with T5 were recovered as a complex with two pre-early phage-coded polypeptides, the 60,000-dalton product of gene A1 and a previously reported 11,000-dalton polypeptide. This RNA polymerase complex had altered transcriptional specificity, in that it transcribed pre-early genes less efficiently than it did early genes.
MeSH terms
DNA-Directed RNA Polymerases; Escherichia coli; Gene Expression Regulation; Genes, Viral; T-Phages; Transcription, Genetic; Viral Proteins
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