Pre-early polypeptides of bacteriophages T5 and BF23.
J Virol, 1977/5;22(2):480-8.
McCorquodale DJ, Shaw AR, Shaw PK, Chinnadurai G
PMID: 325230
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Abstract
Nine pre-early polypeptides have been detected after infection with bacteriophage T5 and 10 pre-early polypeptides have been detected after infection with bacteriophage BF23. Only about one-half of the coding capacity of the redundant ends of the phage DNA, which code for pre-early proteins, is needed for these 9 to 10 pre-early polypeptides. The direction of transcription of pre-early genes A1 and A2 has been established from the size of N-terminal polypeptide fragments induced by amber mutants and from the known intragenic loci of the amber mutations. Some pre-early functions appear to be nonessential, because a viable deletion mutant of BF23 fails to induce three and possibly four of the detectable pre-early polypeptides.
MeSH terms
Coliphages; DNA, Viral; Escherichia coli; Genes; Molecular Weight; Mutation; Peptides; Transcription, Genetic; Viral Proteins
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