Center for Genomic and Personalized Medicine, Guangxi Medical University, 530021, Nanning, Guangxi, China.
Guangxi collaborative innovation center for genomic and personalized medicine, 530021, Nanning, Guangxi, China.
Guangxi key laboratory for genomic and personalized medicine, Guangxi key laboratory of colleges and universities, 530021, Nanning, Guangxi, China.
Institute of Urology and Nephrology, The First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, Guangxi, China.
Department of Urology, The First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, Guangxi, China.
Key Laboratory of Longevity and Aging-related Diseases(Guangxi Medical University), Ministry of Education, Nanning, Guangxi, 530021, P.R. China.
Center for Translational Medicine & School of Preclinical Medicine, Guangxi Medical University, Nanning, Guangxi, 530021, P.R. China.
Department of Urology, Affiliated Tumour Hospital of Guangxi Medical University, 530021, Nanning, Guangxi, China.
Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, Guangxi, China.
Guangxi Key Laboratory of Precision Medicine in Cardio-cerebrovascular Diseases Control and Prevention, 530021, Nanning, Guangxi, China.
Guangxi Clinical Research Center for Cardio-cerebrovascular Diseases, 530021, Nanning, Guangxi, China.
Center for Genomic and Personalized Medicine, Guangxi Medical University, 530021, Nanning, Guangxi, China. chengjiwen1977@foxmail.com.
Guangxi collaborative innovation center for genomic and personalized medicine, 530021, Nanning, Guangxi, China. chengjiwen1977@foxmail.com.
Guangxi key laboratory for genomic and personalized medicine, Guangxi key laboratory of colleges and universities, 530021, Nanning, Guangxi, China. chengjiwen1977@foxmail.com.
Institute of Urology and Nephrology, The First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, Guangxi, China. chengjiwen1977@foxmail.com.
Department of Urology, The First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, Guangxi, China. chengjiwen1977@foxmail.com.
Center for Genomic and Personalized Medicine, Guangxi Medical University, 530021, Nanning, Guangxi, China. mozengnan@gxmu.edu.cn.
Guangxi collaborative innovation center for genomic and personalized medicine, 530021, Nanning, Guangxi, China. mozengnan@gxmu.edu.cn.
Guangxi key laboratory for genomic and personalized medicine, Guangxi key laboratory of colleges and universities, 530021, Nanning, Guangxi, China. mozengnan@gxmu.edu.cn.
Institute of Urology and Nephrology, The First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, Guangxi, China. mozengnan@gxmu.edu.cn.
Department of Urology, The First Affiliated Hospital of Guangxi Medical University, 530021, Nanning, Guangxi, China. mozengnan@gxmu.edu.cn.
A comprehensive cellular anatomy of normal human kidney is crucial to address the cellular origins of renal disease and renal cancer. Some kidney diseases may be cell type-specific, especially renal tubular cells. To investigate the classification and transcriptomic information of the human kidney, we rapidly obtained a single-cell suspension of the kidney and conducted single-cell RNA sequencing (scRNA-seq). Here, we present the scRNA-seq data of 23,366 high-quality cells from the kidneys of three human donors. In this dataset, we show 10 clusters of normal human renal cells. Due to the high quality of single-cell transcriptomic information, proximal tubule (PT) cells were classified into three subtypes and collecting ducts cells into two subtypes. Collectively, our data provide a reliable reference for studies on renal cell biology and kidney disease.
