Adherence ability of Staphylococcus epidermidis on prosthetic biomaterials: an in vitro study.
Int J Nanomedicine, 2013;8:3955-61.
Shida T[1], Koseki H, Yoda I, Horiuchi H, Sakoda H, Osaki M
Affiliations
PMID: 24143100DOI: 10.2147/IJN.S51994
Impact factor: 7.033
Abstract
Bacterial adhesion to the surface of biomaterials is an essential step in the pathogenesis of implant-related infections. In this in vitro research, we evaluated the ability of Staphylococcus epidermidis to adhere to the surface of solid biomaterials, including oxidized zirconium-niobium alloy (Oxinium), cobalt-chromium-molybdenum alloy, titanium alloy, commercially pure titanium, and stainless steel, and performed a biomaterial-to-biomaterial comparison. The test specimens were physically analyzed to quantitatively determine the viable adherent density of the S. epidermidis strain RP62A (American Type Culture Collection [ATCC] 35984). Field emission scanning electron microscope and laser microscope examination revealed a featureless, smooth surface in all specimens (average roughness <10 nm). The amounts of S. epidermidis that adhered to the biomaterial were significantly lower for Oxinium and the cobalt-chromium-molybdenum alloy than for commercially pure titanium. These results suggest that Oxinium and cobalt-chromium-molybdenum alloy are less susceptible to bacterial adherence and are less inclined to infection than other materials of a similar degree of smoothness.
Keywords: bacterial adhesion; implant; infection; surface character
MeSH terms
Bacterial Adhesion; Biocompatible Materials; Equipment Contamination; Materials Testing; Metals; Prostheses and Implants; Staphylococcus epidermidis
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