Full name: transmembrane protein 59

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: C1orf8; DCF1; HSPC001; PRO195; UNQ169

Summary: This gene encodes a protein shown to regulate autophagy in response to bacterial infection. This protein may also regulate the retention of amyloid precursor protein (APP) in the Golgi apparatus through its control of APP glycosylation. Overexpression of this protein has been found to promote apoptosis in a glioma cell line. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

Expression: Ubiquitous expression in colon (RPKM 47.8), prostate (RPKM 39.1) and 25 other tissues

Gene size: 26893bp

Exon count: 9