UNC5C unc-5 netrin receptor C [ Homo sapiens (human) ]
Source: NCBI Gene (ID 8633)
Source: NCBI Gene (ID 8633)
Symbol: UNC5C
Full name: unc-5 netrin receptor C
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: UNC5H3
Summary: This gene product belongs to the UNC-5 family of netrin receptors. Netrins are secreted proteins that direct axon extension and cell migration during neural development. They are bifunctional proteins that act as attractants for some cell types and as repellents for others, and these opposite actions are thought to be mediated by two classes of receptors. The UNC-5 family of receptors mediate the repellent response to netrin; they are transmembrane proteins containing 2 immunoglobulin (Ig)-like domains and 2 type I thrombospondin motifs in the extracellular region. [provided by RefSeq, Jul 2008]
Expression: Broad expression in thyroid (RPKM 2.7), adrenal (RPKM 2.7) and 21 other tissues
Orthologs: mouse
Gene size: 386470bp
Exon count: 20