Full name: Rho GTPase activating protein 22

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: RhoGAP2; RhoGap22

Summary: This gene encodes a member of the GTPase activating protein family which activates a GTPase belonging to the RAS superfamily of small GTP-binding proteins. The encoded protein is insulin-responsive, is dependent on the kinase Akt and requires the Akt-dependent 14-3-3 binding protein which binds sequentially to two serine residues. The result of these interactions is regulation of cell motility. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Expression: Low expression observed in reference dataset

Gene size: 226435bp

Exon count: 22