CHMP1B charged multivesicular body protein 1B [ Homo sapiens (human) ] - Gene - Data resources

57132

CHMP1B charged multivesicular body protein 1B [ Homo sapiens (human) ]
Source: NCBI Gene (ID 57132)

Symbol: CHMP1B

Full name: charged multivesicular body protein 1B

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: C10orf2; C18-ORF2; C18orf2; CHMP1.5; Vps46-2; Vps46B; hVps46-2

Summary: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]

Orthologs: mouse

Gene size: 3032bp

Exon count: 1