Aim2 absent in melanoma 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 383619)
Source: NCBI Gene (ID 383619)
Symbol: Aim2
Full name: absent in melanoma 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Gm1313; Ifi210
Summary: Enables double-stranded DNA binding activity and identical protein binding activity. Involved in positive regulation of macromolecule metabolic process; pyroptosis; and regulation of defense response. Acts upstream of or within cellular response to interferon-beta. Located in cytoplasm. Part of AIM2 inflammasome complex. Orthologous to human AIM2 (absent in melanoma 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in spleen adult (RPKM 1.0), CNS E11.5 (RPKM 0.8) and 22 other tissues
Orthologs: human
Gene size: 116502bp
Exon count: 18