Full name: fatty acid 2-hydroxylase

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: FAAH; Faxdc1; G630055L08Rik

Summary: Enables fatty acid alpha-hydroxylase activity. Involved in galactosylceramide biosynthetic process; glucosylceramide biosynthetic process; and plasma membrane raft organization. Acts upstream of or within several processes, including lipid modification; myelin maintenance; and sebaceous gland cell differentiation. Located in endoplasmic reticulum. Is expressed in back skin; sebaceous gland; skin; and vibrissa. Used to study hereditary spastic paraplegia 35. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 35. Orthologous to human FA2H (fatty acid 2-hydroxylase). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Biased expression in stomach adult (RPKM 77.1), colon adult (RPKM 59.1) and 8 other tissues

Gene size: 48684bp

Exon count: 7