Full name: glycosylphosphatidylinositol specific phospholipase D1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: GPIPLD; GPIPLDM; PIGPLD; PIGPLD1; PLD

Summary: Many proteins are tethered to the extracellular face of eukaryotic plasma membranes by a glycosylphosphatidylinositol (GPI) anchor. The GPI-anchor is a glycolipid found on many blood cells. The protein encoded by this gene is a GPI degrading enzyme. Glycosylphosphatidylinositol specific phospholipase D1 hydrolyzes the inositol phosphate linkage in proteins anchored by phosphatidylinositol glycans, thereby releasing the attached protein from the plasma membrane. [provided by RefSeq, Jul 2008]

Expression: Biased expression in liver (RPKM 12.6), skin (RPKM 4.0) and 8 other tissues

Gene size: 71319bp

Exon count: 27