Chmp1a charged multivesicular body protein 1A [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 234852)
Symbol: Chmp1a
Full name: charged multivesicular body protein 1A
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 2900018H07Rik; Pcoln3
Summary: Predicted to enable protein domain specific binding activity and protein homodimerization activity. Predicted to be involved in several processes, including midbody abscission; mitotic sister chromatid segregation; and regulation of cell cycle process. Predicted to be located in early endosome; microtubule organizing center; and nuclear lumen. Predicted to be part of ESCRT III complex. Predicted to be active in multivesicular body. Is expressed in 4th ventricle choroid plexus; 4th ventricle choroid plexus epithelium; cerebellum; cerebellum Purkinje cell layer; and cortical plate. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 8. Orthologous to human CHMP1A (charged multivesicular body protein 1A). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in colon adult (RPKM 82.2), large intestine adult (RPKM 63.6) and 28 other tissues
Orthologs: human
Gene size: 8528bp
Exon count: 7