Full name: serine and arginine-rich splicing factor 7

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: 35kDa; 9430065L19Rik; 9G8; NX-96; Sfrs7

Summary: The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Multiple protein-coding and non-protein-coding transcript variants have been found for this gene. [provided by RefSeq, Apr 2022]

Expression: Broad expression in CNS E11.5 (RPKM 98.8), CNS E14 (RPKM 77.4) and 22 other tissues

Gene size: 7290bp

Exon count: 9