AP2A2 adaptor related protein complex 2 subunit alpha 2 [ Homo sapiens (human) ] - Gene - Data resources

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AP2A2 adaptor related protein complex 2 subunit alpha 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 161)

Symbol: AP2A2

Full name: adaptor related protein complex 2 subunit alpha 2

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ADTAB; CLAPA2; HIP-9; HIP9; HYPJ

Summary: The protein encoded by this gene is a subunit of the AP-2 adaptor protein complex, which is involved in linking lipid and protein membrane components with the clathrin lattice. This interaction supports the formation of clathrin-coated vesicles, and the encoded subunit aids in the process by binding polyphosphoinositide-containing lipids in the cell membrane. [provided by RefSeq, Nov 2016]

Expression: Ubiquitous expression in spleen (RPKM 30.8), brain (RPKM 22.0) and 25 other tissues

Orthologs: mouse

Gene size: 86371bp

Exon count: 29