STOmics technology:BGI Stereomics Stereo-Seq

Data type:Spatial transcriptomics

Sample scope:Multiisolate

Summary:This study investigates how maternal microbiota exposure is associated with brain and neuroendocrine development in piglets. Using germ-free and maternal microbiota-transplanted piglet models, we generated an integrated multi-organ dataset combining single-nucleus RNA sequencing, spatial transcriptomics, intestinal bulk RNA sequencing, and metabolomics. The dataset covers five brain regions, the hypothalamic-pituitary-adrenal axis, and multiple intestinal segments, providing a resource for investigating microbiota-associated cellular, transcriptional, spatial, and metabolic changes during early postnatal development.

Contributor(s):Leli Wang.

Submitter:王乐莅(LEli Wang),Chinese Academy of Sciences

Release date:2026-09-21

Updated:2026-09-21