MHAOD: Macaque Hypothalamus Atlas for Obesity and Diabetes

This website offers an open and interactive database for interrogation of snRNA-seq dataset and stereo-seq maps in macaque hypothalamus. Its comprehensive single-cell transcriptomic atlas provides valuable insights into the molecular changes of individual cells in various hypothalamic regions in control, obese and type 2 diabetic macaques. As a result, researchers studying metabolic disorders such as diabetes and obesity can use this resource to enhance their understanding of the molecular mechanisms that underlie such conditions.

Release at 2024-02-06

Lei, Ying et al. “Region-specific transcriptomic responses to obesity and diabetes in macaque hypothalamus.” Cell metabolism vol. 36,2 (2024): 438-453.e6. DOI: 10.1016/j.cmet.2024.01.003