Project name: Streptococcus mutans

Description: In vitro comparative transcriptome analysis was carried to determine genes that are differentially expressed in S. mutans biofilm compared with free-living cells. DNA-microarray analyses indicated that about 12 % of genes showed significant differential expression: 139 were activated and 104 were repressed in biofilm vs. planktonic environment.Keywords: cell type comparisonOverall design: S. mutans UA159 was grown to stationary phase planktonic bacteria and the biofilm generated on polystyrene multidishes. the total RNA was extracted and, after Reverse transcription and probe labeling, Hybridized to DNA-microarray.

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: Medical

Release date: 2007-05-07

Last updated: 2007-01-14