Comparison of Longitudinal Leukocyte Gene Expression after Burn Injury or Trauma Hemorrhage in Mice
Source: NCBI BioProject (ID PRJNA97899)
Source: NCBI BioProject (ID PRJNA97899)
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Project name: Mus musculus
Description: We report here the genes that are sequentially expressed in white blood cells from blood and spleen at 2 hours, 2 day,3 days, and 7 days after burn and sham injury or trauma-hemorrhage (T-H) and sham T-H. Includes WBC treated with LPS for 2 hours and 1 day.Overall design: White blood cells (WBC) and splenocytes were harvested from individual mice and RNA was extracted, labeled and hybridized to Affymetrix Mouse Genome 430 2.0 GeneChips™. The results were analyzed by dCHIP and BRB Array Tools software. Ingenuity Pathway Analysis (IPA) was applied to identify molecular networks significantly affected by the injuries.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Burn & Trauma Research, Department of Surgery, Massachusetts General Hospital
Literatures
- PMID: 17986522
Release date: 2007-03-31
Last updated: 2007-03-29