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PRJNA95799
Expression profiling of T. rubrum treated with amphotericin B and ketoconazole
Source: NCBI BioProject (ID PRJNA95799)

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Project name: Trichophyton rubrum
Description: Two antifungal agents, ketoconazole (KTZ) and amphotericin B (AMB), have specific activity against dermatophytes.A cDNA microarray was constructed from the expressed sequence tags (ESTs) of different developmental stages, and transcriptional profiles of the responses to KTZ and AMB were determined. Some class-specific and mechanism-independent changes in gene expression were found.Keywords: comparison of expression statusOverall design: The expression profiles of Trichophyton rubrum treated with AMB and KTZ were compared to those of Trichophyton rubrum without drug. Each treatment has three replicates.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: State Key Lab of Virus Gene Engineering
Literatures
  1. PMID: 17060531
Release date: 2007-05-30
Last updated: 2006-06-07