Project name: Effect of ppGpp on Salmonella Typhimurium gene expression

Description: The expression profile of an S. Typhimurium mutant strain unable to synthesise ppGpp (relAspoT deletions) was compared to the wild-type strain. The effect of ppGpp on virulence gene expression was studied under 4 different growth conditions that induce virulence gene expression.Keywords: genetic modificationOverall design: Study comprised 4 separate experiments (with 2 strains and 4 replicates for each strain per growth condition). The experiments were indirect comparisons using Salmonella genomic DNA as the comparator which also acted as the control for spot quality.

Data type: Transcriptome or Gene expression

Sample scope: Multispecies

Relevance: Medical

Release date: 2006-05-30

Last updated: 2006-04-07