Project name: Homo sapiens

Description: Anticancer drug clustering in lung cancer based on gene expression profiles.We performed gene expression analysis in lung cancer cell lines. (used: Affymetrix GeneChip Human Genome U133 Array Set HG-U133A).We also examines the sensitivity of these cell lines to commonly used anti-cancer agents (docetaxel, paclitaxel, gemcitabine, vinorelbine, 5-FU, SN38, cisplatin, and carboplatin) via MTT assay.We related the cytoxic activity of each of these agents to corresponding expression pattern in each of the cell lines using modified NCI program.Keywords: cytotoxicity, lung cancer, anticancer drugsOverall design: gene expression analysis in lung cancer cell lines

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: Medical

Release date: 2006-02-10

Last updated: 2006-01-30