Polysomal, free mRNP, and total cellular mRNA of J774.1 before and after LPS stimulation
Source: NCBI BioProject (ID PRJNA94783)
Source: NCBI BioProject (ID PRJNA94783)
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Project name: Mus musculus
Description: Bacterial lipopolysaccharide(LPS) dramatically activates macrophages. So far, dozen of papers indicated that many proinflammatory molecules are transcriptionaly regulated during response. Despite of this,translational regulation is not fully elucidated especially in a comprehensive fashion. In this series, we investigated expression profiles of translation active (polysome) inactive (free mRNP) mRNAs of a typical mouse macrophage cell line, J774.1. Moreover, we also measured total cellular RNA level as a reference.Keywords: time-courseOverall design: Triplicates for each time points are included.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Laboratory for Veterinary Physiology, School of Veterinary Medicine, Rakuno Gakuen University
Literatures
- PMID: 18230670
Release date: 2008-02-05
Last updated: 2006-02-21