Project name: Saccharomyces cerevisiae

Description: Purpose of profiling experiment was to examine effects of a mutation of a subunit of TFIIH, ssl1p, which has ubiquitin ligase activity.The whole complex has previously been shown to have both kinase and helicase activities. We wanted to see if 1) there weregeneral transcriptional defects with these mutations, as there are with other mutations to kinase activity, and 2) if therewere transcriptional effects on DNA repair machinery when the mutants were treated with MMS, which is an alkylating agent.Keywords: other

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: ModelOrganism

Release date: 2005-04-20

Last updated: 2005-02-25