Genome-wide CRISPR screen to identify modulators of POLQ inhibition in SUM149PT
Source: NCBI BioProject (ID PRJNA880040)

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Description: SUM149PT were transduced with a genome-wide CRISPR ko library (TKO v3), following a 7 day selection period. Then, cells were treated with DMSO or 2-2.5uM of POLQ inhibitor for 18 days. 3 samples were sequenced:- early time point (after 5 days of puromycin selection)- end time point DMSO (after 18 days of treatment with DMSO)- end time point POLQi (after 18 days of treatment with POLQi)
Data type: raw sequence reads
Sample scope: Multispecies
Relevance: Other
Organization: Research Center for Molecular Medicine
Last updated: 2022-09-13
Statistics: 3 samples; 3 experiments; 3 runs