Project name: Profiling mRNA, miRNA and lncRNA expression changes in endothelial cells in response to increasing doses of ionizing radiation [RNA-seq]

Description: RNA seq for lncRNA and mRNA differential expression analysis, and small RNA seq for miRNA differential expression analysis were performed in primary human aotic endothelial cells treated with increasing doses of radiation (1 Gy, 2 Gy, 4 Gy, 8 Gy and 10 Gy). Total RNA was collected 24 h and 72 h after radiation. Comparisons were made with unirradiated cells plated for 24 h and 72 h repsectively.Overall design: 0 Gy-24h (3), 1 Gy-24h (3), 2 Gy-24h (3), 4 Gy-24h (3), 8 Gy-24h (3), 10 Gy-24h (3); 0 Gy-72h (3), 1 Gy-72h (3), 2 Gy-72h (3), 4 Gy-72h (3), 8 Gy-72h (3), 10 Gy-72h (3)

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: Medical

Last updated: 2022-05-03