Project name: Trichophyton benhamiae

Description: Millions of humans and animals suffer from superficial infections caused by a group of highly specialized filamentous fungi, the dermatophytes. To provide broad insights into the molecular basis of biological and/or pathogenicity associated traits, the interaction of the Arthroderma benhamiae, a common member of this group, with human keratinocytes was studied by transcriptome profiling. ESTs from fungal cells grown with and without keratinocytes were sequenced using the Roche/454 platform and mapped to the A. benhamiae genome to determine expression levels. Based on the results a set of differentially expressed genes was compiled for further study of the mechanisms of infection in dermatophytes. Details of this study are provided in Burmester et al. 2010 (submitted).

Data type: Transcriptome or Gene expression

Sample scope: Monoisolate

Last updated: 2011-12-20