Transcriptional Changes Associated with Acute to Chronic Stage Muscle Adaptations in a Model of Rotator Cuff Tendon Tear
Source: NCBI BioProject (ID PRJNA724734)
Source: NCBI BioProject (ID PRJNA724734)
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Project name: Transcriptional Changes Associated with Acute to Chronic Stage Muscle Adaptations in a Model of Rotator Cuff Tendon Tear
Description: In this study, we collected rabbit supraspinatus muscle tissue with higher temporal resolution (1, 2, 4, 8, 16 weeks) post-tenotomy (n=6/group), where muscle degeneration occurs at later time points, to determine if transcriptional changes occur. RNA sequencing and analyses were performed using standard techniques to identify a transcriptional timeline of rotator cuff muscle changes and related morphological sequelae.Overall design: rotator cuff muscle mRNA after tenotomy injury at 1, 2, 4, 8, 16 weeks post-tenotomy
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Muscle Physiology, Orthopaedic Surgery, Radiology, and Bioengineering, University of California San Diego
Literatures
- PMID: 34421646
Last updated: 2021-04-23