Project name: Aspergillus fumigatus

Description: Lines evolved for resistance to SI fungicides were whole genome sequenced to uncover the genetic underpinning of phenotypic differences found. Lines that showed increased resistance to environmentally used fungicides, also show increased resistance against medically used fungicides. The increases of this resistance in evolutionary times could be explained by mutations found in genes previously described to confer fungicide resistance as well as in genes previuously not described to confer resistance.

Data type: genome sequencing

Sample scope: Monoisolate

Relevance: Medical

Last updated: 2017-09-01