Vitrification alters fetal development by profound differences during fetal placenta formation
Source: NCBI BioProject (ID PRJNA221617)

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Project name: Oryctolagus cuniculus
Description: Vitrification is replacing slow freezing as the most popular method for human embryo cryopreservation in clinics world-wide. Several studies demonstrated that cryopreservation alters gene expression of mammalian embryos, but none of them analysed what happen with those embryos that get implanted and follow with the gestation. The aim of this study was to evaluate the effect of vitrification technique on rabbit embryonic and fetal development by performing a transcriptomic analysis of 6 day old embryos and 14 days old fetal placentas.Overall design: Effect of vitrification on late blastocyst and fetal placenta transcriptome. Four indepent replicates were performed for each condition (control and vitrified) and for both tissues (embryo and fetal placenta).
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Biotechnology of Reproduction, Animal Science, Universidad Politécnica Valencia
Literatures
  1. PMID: 24534948
Last updated: 2013-09-26