Project name: Mus musculus

Description: An assessment of a role of Ebf1 in committed B lineage cells.In this study, we adopted the strategy of deleting Ebf1 after reconstitution of Rag2-/-Il2rg-/- mice and found that committed pre-B cells could be converted into T cells and ILCs upon deletion of Ebf1.Overall design: We used µ-arrays to gain insight into changes in gene expression of CD19+ Ebf1-deficient cells.The dataset was compared with microarray data available for different hematopoietic developmental stages (GSE15907).The complete dataset is linked below as a supplementary file.

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: ModelOrganism

Last updated: 2013-04-24