Phrenic neuron determinant gain-of-function screen in M. musculus ES cell-derived motor neurons
Source: NCBI BioProject (ID PRJNA196415)
Source: NCBI BioProject (ID PRJNA196415)
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Project name: Mus musculus
Description: Expression response after induction of putative phrenic neuronal determinants in ES cell-derived motor neurons was compared to a pre-determined list of genes over-expressed in FACS-sorted primary.Transcription factor Pou3f1 was identified as a major determinant of phrenic identity.Overall design: Expression in induced cell lines were compared to YFP controls, and over-representation of phrenic genes was computed for the list of differentially expressed genes in each indiced cell lines.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: MRC Centre for Developmental Neurobiology, King's College London
Literatures
- PMID: 24496616
Last updated: 2013-04-05