Transcriptome-profiling (RNA-seq) and Ribosome-profiling (Ribo-seq) of BJ cells treated with Nutlin-3a, an MDM2 inhibitor, which induces p53.
Source: NCBI BioProject (ID PRJNA196335)
Source: NCBI BioProject (ID PRJNA196335)
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Project name: Homo sapiens
Description: We applied in parallel RNA-Seq and Ribosome-profiling analyses to immortalized human primary BJ fibroblast cells in which p53 was induced by Nutlin-3aOverall design: RNA-seq, using Illumina HiSeq 2000, was applied to BJ cells treated with Nutlin-3a, at 5 timepoints: 0, 2, 4, 6, 19 hrsRibosome profiling was applied to BJ cells treated with Nutlin-3a, at 5 timepoints: 0, 2, 4, 6, 19 hrs
Data type: Other
Sample scope: Multiisolate
Relevance: Medical
Organization: Human Genetics, Tel Aviv University
Literatures
- PMID: 23594524
Last updated: 2013-04-04