Deletion of the NF-κB subunit p65/RelA in the hematopoietic compartment leads to defects in hematopoietic stem cell function.
Source: NCBI BioProject (ID PRJNA196174)
Source: NCBI BioProject (ID PRJNA196174)
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Project name: Mus musculus
Description: Deletion of the NF-κB subunit p65/RelA in the hematopoietic compartment results in gene expression changes in lineage-Flk2-c-kit+Sca-1+ cells from mouse bone marrow.Overall design: We analyzed lineage-Flk2-c-kit+Sca-1+ cells from the bone marrow of p65 wild-type or knockout mice using the Affymetrix Mouse Exon 1.0 ST platform. Array data was processed by Affymetrix Exon Array Computational Tool. No technical replicates were performed.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: ModelOrganism
Organization: Baldwin, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill
Literatures
- PMID: 23670180
Last updated: 2013-04-03