Gene expression regulation by miR-145 in pancreatic cancer
Source: NCBI BioProject (ID PRJNA193312)
Source: NCBI BioProject (ID PRJNA193312)
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Project name: Homo sapiens
Description: miR-145 is a tumor suppressor miRNA in various malignancies including pancreatic cancer. Identification of miR-145 targets can lead to more understanding of the development of pancreatic cancer. Therefore, in this project, we aimed to characterize the changes of transcriptomes caused by miR-145 to identify more miR-145 target transcripts.Overall design: cDNA microarray was used to compare transcriptomes 48 hr after transfection of miR-145 mimics or control scramble RNA in a pancreatic cancer cell line, Mia-PaCa2.
Data type: Transcriptome or Gene expression
Sample scope: Multiisolate
Relevance: Medical
Organization: Akhilesh Pandey, Institute of Genetic Medicine, Johns Hopkins University School of Medicine
Last updated: 2013-03-18