Project name: Mus musculus

Description: A novel knock-in mouse model was reported (Minella et al., Genes Devel 2008) to have a mixed hyper-proliferative and defective maturation phenotype in the erythroid series. Microarray analyses were performed to identify gene expression alterations resulting from dysregulated cyclin E control. Overall design: Analysis of gene expression changes in cyclin E (T74A T393A) knock-in erythroblasts (Ter119-positive, CD71-high) isolated by FACS sorting. Comparison is to cells similarly isolated from littermate controls.

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: ModelOrganism

Last updated: 2013-03-13