Project name: Macaca mulatta

Description: The role of CD1-restricted, lipid-specific T cells in vivo remains to be elucidated.We used microarrays to detail the global program of gene expression accompanied by the activation of CD1-restricted, lipid-specific T cells.Overall design: Monkeys were immunized with BCG bacteria to evoke CD1-restricted, mycolyl glycolipid-specific T cell responses at high frequency. The PBMCs were stimulated in the presense or absense of mycolyl glycolipid antigen, followed by RNA extraction and hybridization on Affymetrix microarrays.

Data type: Transcriptome or Gene expression

Sample scope: Multiisolate

Relevance: ModelOrganism

Last updated: 2013-03-07