Sodium arsenite induced DNA methylation changes in A549 human epithelial lung carcinoma cells
Source: NCBI BioProject (ID PRJNA188955)

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Project name: Homo sapiens
Description: Arsenic is methylated during its metabolism, thereby depleting the intracellular methyl donor S-adenosyl-methionine, which may lead to disturbances in DNA methylation patternsOverall design: Cells were exposed to sodium arsenite (NaAsO2, Sigma) at concentrations of 0.08 µM, 0.4 µM and 2 µM for 1, 2 and 8 weeks. A549 arsenic dose time response study.
Data type: Epigenomics
Sample scope: Multiisolate
Relevance: Medical
Organization: Toxicogenomics, Maastricht University
Literatures
  1. PMID: 25199682
Last updated: 2013-02-08